Vedolizumab immunogenicity was assessed using an enzyme-linked immunosorbent assay (ELISA) with ~ 0.5 ug / mL drug disorders, which may underestimate the on-drug immunogenicity. We aimed to compare the results between ELISA and immunogenicity of a new drug-tolerant electrochemiluminescence (ECL) assay (and two versions of neutralizing tests, drug-sensitive to the drug-tolerant). ECL assay drug tolerance […]Continue Reading
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Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega.
Multiple sequence alignments are fundamental to many methods of sequence analysis. Most alignments computed using a heuristic progressive alignment. This method began to be a bottleneck in some pipeline analysis when dealing with thousands of sequence data set size. Some methods allow the calculation of a larger set of data while sacrificing quality, and others […]Continue Reading