19 listopada, 2020
Antibodies, Assay Kits, Biology Cells, cDNA, Culture Cells, Devices, DNA, Dna Testing, Elisa Kits, Equipments, Gels, Isotypes, NATtrol, Panel, Particles, PCR, Pcr Kits, Peptides, Reagents, Recombinant Proteins, Ria Kits, Test Kits, Uncategorized, Vector & Virus, Western Blot
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Comparison of the ELISA and ECL Assay for Vedolizumab Anti-drug Antibodies: Assessing the Impact on Pharmacokinetics and Safety Outcomes of the Phase 3 GEMINI Trials

Vedolizumab immunogenicity was assessed using an enzyme-linked immunosorbent assay (ELISA) with ~ 0.5 ug / mL drug disorders, which may underestimate the on-drug immunogenicity. We aimed to compare the results between ELISA and immunogenicity of a new drug-tolerant electrochemiluminescence (ECL) assay (and two versions of neutralizing tests, drug-sensitive to the drug-tolerant).

ECL assay drug tolerance is ~ 100 times higher than the ELISA (≥ 50 mg / mL vs 0.5 ug / mL to 500 ng / mL positive control), and the sensitivity of the test is <5 ng / mL for both tests. Vedolizumab immunogenicity rated at 2000 GEMINI 1 and 2 patients initially tested by ELISA and retested by the ECL assay. anti-drug antibodies (ADA) results in infusion-related reactions-and pharmacokinetic (PK) was examined using descriptive statistics and population PK analysis.

With the ECL assay, 6% (86/1427) of patients treated with vedolizumab as induction and maintenance therapy ADA-positive tested. Of these, 20 patients with persistent positive and 56 had a neutralizing antibody. By ELISA, 4% (56/1434) of this ADA-positive patients, 9 were constantly positive, and 33 have antibodies. Among 61 patients with infusion-related reactions, 6 (10%) is ADA-positive (2 continuous positive) by ECL assay. By ELISA, 3 (5%) both ADA-positive patients and constantly positive.

Partial results (96%) was similar in both tests. In a population PK models are updated, ADA-positive status is expected to increase linearly vedolizumab clearance by a factor of 1.10 (95% credible interval 1.03 to 1.17), consistent with previous reports. ADA impacts the safety and PK modeling generally remained consistently good using ELISA or ECL assay.

Antitumor effect of humanized anti-tissue factor antibody-drug conjugate in a model of peritoneal disseminated pancreatic cancer

tissue factor (TF) is an attractive target for cancer therapy due to excess in some kinds of malignancies. Additionally, TF has been reported to play a functional role both in the development of cancer and metastasis. Several groups have developed antibody-drug conjugate (ADC) to the TF to be used as a cancer treatment, and has demonstrated efficacy in subcutaneous xenograft models of conventional and patient-derived xenograft model.

However, no previous studies have investigated the effectiveness of anti-TF ADC model with advanced cancer. This study developed the original anti-human TF monoclonal antibody conjugated to monomethyl auristatin E, and evaluated its efficacy in vivo in a xenograft model of pancreatic cancer with peritoneal dissemination. An in vitro study showed that the anti-TF ADC has a strong binding affinity and cytotoxic activity against human pancreatic cancer cells highly expressed TF antigen.

Anti-TF ADC also show greater antitumor effect than the ADC control in the conventional subcutaneous xenograft models, with efficacy depends on TF expression in the tumor tissue. Furthermore, the anti-TF ADC significantly inhibited tumor growth in an orthotopic xenograft model, and extend the lifespan in a murine model of peritoneal dissemination. These results suggest that anti-TF ADC has the potential to be an effective treatment not only for the primary tumor, but also for those who disseminated widely. Therefore, it can be concluded that the ADC targeting TF may be a promising agent for the treatment of advanced pancreatic cancer.

 

Treatment of Antibody-Mediated Rejection After Kidney Transplant: Effects immunology, clinical response, and histologic findings

BACKGROUND antibody-mediated rejection (AMR) prize with clinical manifestations are diverse and may have a potential negative impact on graft function and survival. If not treated successfully, AMR can lead to a 20-30% loss of the graft after one year. Little is known about the efficacy of the treatment of the AMR, and the most appropriate treatment strategy has not been determined.

This study evaluated the effects of AMR treatment with plasmapheresis (PP) and intravenous immunoglobulin (IVIG) on renal function, the intensity of anti-HLA antibodies, and graft biopsy morphology. MATERIALS AND METHODS retrospective cohort study of this center including AMR kidney transplant recipients with biopsy treated with PP and / or IVIG. clinical findings, mean fluorescence intensity of donor-specific antibodies anti-HLA (DSA), and graft histology findings, classified according to the Park scored at the time of AMR and 6 and 12 months later, were evaluated.

Results Of the 42 patients who met the inclusion criteria, 38 (90.5%) received IVIG and 26 (61.9%) underwent PP. At AMR diagnosis, 36 (85.7%) patients had proteinuria, with an estimated glomerular filtration rate they remained stable during follow-up. During the first year, 8 (19.0%) patients experienced graft failure, but did not die with a functioning graft. The decline of class I panel reactive antibodies were observed 6 and 12 months after treatment AMR, with a significant reduction in the DSA-A and -B fluorescence intensity, but there is no change in the DSA-DQ. Graft biopsy showed a reduction in inflammation and score C4D, without any improvement in microvascular inflammation. CONCLUSION AMR reduce treatment related biopsy and serological markers AMR, but does not affect the DSA-DQ.

Tryptophan Oxidation of Monoclonal Antibody under Various Conditions Oxidative Stress: Preparation oxidative Specific Favor Unlike tryptophan residue

oxidation of tryptophan could play an important role in choosing a therapeutic monoclonal antibody for commercialization. Monoclonal antibodies that harbor very sensitive tryptophan residue is usually discarded in favor of antibodies oxidation resistance.

Tryptophan residue individual susceptibility to oxidation is usually evaluated through the forced degradation studies during the development process of molecules. We compared the results of some general forced degradation „stress test” for any tryptophan residues in the monoclonal antibody and found that the oxidation state of high stress consistently give different ratings across the tryptophan residue oxidative sensitivity of individuals compared with long-term thermal stability or low stress conditions. We then determined that this difference in ranking is largely due to an overabundance of double oxidation (ie detected as 32 Da) specific tryptophan residue under high stress conditions as compared to a single oxidation (ie 16 Da).

AXL Mouse mAb
E2220240 100ul
EUR 225
Description: Available in various conjugation types.

AXL Mouse mAb
E2220307 100ul
EUR 225
Description: Available in various conjugation types.

AXL Mouse mAb
E2222074 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

AXL Mouse mAb
MBS8538450-01mL 0.1mL
EUR 305

AXL Mouse mAb
MBS8538450-01mLAF405L 0.1mL(AF405L)
EUR 565

AXL Mouse mAb
MBS8538450-01mLAF405S 0.1mL(AF405S)
EUR 565

AXL Mouse mAb
MBS8538450-01mLAF610 0.1mL(AF610)
EUR 565

AXL Mouse mAb
MBS8538450-01mLAF635 0.1mL(AF635)
EUR 565

AXL Mouse mAb
MBS8538517-01mL 0.1mL
EUR 305

AXL Mouse mAb
MBS8538517-01mLAF405L 0.1mL(AF405L)
EUR 565

AXL Mouse mAb
MBS8538517-01mLAF405S 0.1mL(AF405S)
EUR 565

AXL Mouse mAb
MBS8538517-01mLAF610 0.1mL(AF610)
EUR 565

AXL Mouse mAb
MBS8538517-01mLAF635 0.1mL(AF635)
EUR 565

AXL siRNA (Mouse)
MBS8238685-15nmol 15nmol
EUR 405

AXL siRNA (Mouse)
MBS8238685-30nmol 30nmol
EUR 565

AXL siRNA (Mouse)
MBS8238685-5x30nmol 5x30nmol
EUR 2450

Anti-Mouse Axl Antibody
103-M158 100 µg
EUR 399
Description: Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt), and Mer (human and mouse homologues of chicken cEyk) constitute a subfamily of the receptor tyrosine kinases (1, 2). The extracellular domains of these proteins contain two Iglike motifs and two fibronectin type III motifs. This characteristic topology is also found in neural cell adhesion molecules and in receptor tyrosine phosphatases. The mouse Axl cDNA encodes an 888 amino acid (aa) precursor that includes an 18 aa signal sequence, a 427 aa extracellular domain, a 21 aa transmembrane segment, and a 422 aa cytoplasmic domain. The extracellular domains of mouse and human Axl share 81% aa sequence identity. These receptors bind the vitamin Kdependent protein growth arrest specific gene 6 (Gas6) which is structurally related to the anticoagulation factor protein S. Binding of Gas6 induces receptor autophosphorylation and downstream signaling pathways that can lead to cell proliferation, migration, or the prevention of apoptosis (3). This family of tyrosine kinase receptors is involved in hematopoiesis, embryonic development, tumorigenesis, and regulation of testicular functions.

Axl (untagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 3, (10ug)
MC221635 10 µg Ask for price

Axl (untagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 2, (10ug)
MC222378 10 µg Ask for price

Axl (untagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 1, (10ug)
MC222408 10 µg Ask for price

Mouse AXL Antibody Pair Set
ABPR-ZB130 5 plates, 15 plates Ask for price
Description: Quantitative determination of Mouse AXL

Mouse Axl Antibody (N-term)
MBS9213070-008mL 0.08mL
EUR 210

Mouse Axl Antibody (N-term)
MBS9213070-04mL 0.4mL
EUR 430

Mouse Axl Antibody (N-term)
MBS9213070-5x04mL 5x0.4mL
EUR 1910

Axl (GFP-tagged) - Mouse AXL receptor tyrosine kinase (Axl) transcript variant 2, (10ug)
MG222556 10 µg Ask for price

Axl (GFP-tagged) - Mouse AXL receptor tyrosine kinase (Axl) transcript variant 3, (10ug)
MG222558 10 µg Ask for price

Axl (Myc-DDK-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 1
MR211073 10 µg Ask for price

Axl (Myc-DDK-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 2
MR222556 10 µg Ask for price

Axl (Myc-DDK-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 3
MR222558 10 µg Ask for price

Mouse AXL ELISA Kit
E28L0663 96T
EUR 666.67

Mouse AXL ELISA Kit
EK5264 96 tests
EUR 599

Mouse AXL ELISA Kit
LF-EK50868 1×96T
EUR 777.6

Mouse AXL ELISA Kit
MBS824634-5x96Tests 5x96Tests
EUR 2880

Mouse AXL ELISA Kit
MBS824634-96Tests 96Tests
EUR 645

Anti-AXL Mouse mAb
MBS475905-01mL 0.1mL
EUR 450

Anti-AXL Mouse mAb
MBS475905-5x01mL 5x0.1mL
EUR 1540

Mouse AXL shRNA Plasmid
20-abx973661
  • Ask for price
  • Ask for price
  • 150 µg
  • 300 µg

Mouse Monoclonal Antibody to AXL
MAB-606020332 0.1ml
EUR 280

Mouse Monoclonal Antibody to AXL
sAP-0203 50ug
EUR 270

Mouse Monoclonal Antibody to AXL
sAP-0273 50ug
EUR 270

Axl (NM_009465) Mouse Recombinant Protein
E45M44931M5 20 ug
EUR 1924.54

Mouse Monoclonal Antiobody to AXL
MAB-606020250 0.1ml
EUR 260

Mouse Monoclonal Anti-Human AXL protein IgG-Biotinylated
AXL13-BTN 100 ul
EUR 634.8

Rat Monoclonal anti-mouse Axl
mAP-0022 100ug
EUR 250

Mouse Monoclonal Anti-Human AXL protein IgG, aff pure
AXL13-M 100 ul
EUR 578.4

anti- AXL antibody
FNab00754 100µg
EUR 606.3
Description: Antibody raised against AXL

Mouse AXL Protein, His Tag
E40MOP1139 20ug
EUR 495

Lenti ORF clone of Axl (mGFP-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 1
MR211073L2 10 µg Ask for price

Lenti ORF clone of Axl (mGFP-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 1
MR211073L4 10 µg Ask for price

Lenti ORF clone of Axl (mGFP-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 2
MR222556L4 10 µg Ask for price

Lenti ORF clone of Axl (mGFP-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 3
MR222558L4 10 µg Ask for price

Mouse AXL PicoKine ELISA Kit
MBS177136-5x96StripWells 5x96-Strip-Wells
EUR 2755

Mouse AXL PicoKine ELISA Kit
MBS177136-96StripWells 96-Strip-Wells
EUR 600

Axl ORF Vector (Mouse) (pORF)
ORF039463 1.0 ug DNA
EUR 607.2

Axl ORF Vector (Mouse) (pORF)
ORF039464 1.0 ug DNA
EUR 607.2

Axl ORF Vector (Mouse) (pORF)
ORF039465 1.0 ug DNA
EUR 607.2

Anti-AXL Antibody, Mouse Monoclonal
MBS8102087-01mL 0.1mL
EUR 300

Anti-AXL Antibody, Mouse Monoclonal
MBS8102087-5x01mL 5x0.1mL
EUR 1200

Anti-AXL Antibody, Mouse Monoclonal
MBS8102088-01mL 0.1mL
EUR 300

Anti-AXL Antibody, Mouse Monoclonal
MBS8102088-5x01mL 5x0.1mL
EUR 1200

Anti-AXL Antibody, Mouse Monoclonal
MBS8102090-01mL 0.1mL
EUR 300

Anti-AXL Antibody, Mouse Monoclonal
MBS8102090-5x01mL 5x0.1mL
EUR 1200

Lenti ORF clone of Axl (Myc-DDK-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 1
MR211073L1 10 µg Ask for price

Lenti ORF clone of Axl (Myc-DDK-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 1
MR211073L3 10 µg Ask for price

Lenti ORF clone of Axl (Myc-DDK-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 2
MR222556L3 10 µg Ask for price

Lenti ORF clone of Axl (Myc-DDK-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 3
MR222558L3 10 µg Ask for price

AXL ELISA Kit (Mouse) (OKBB00412)
OKBB00412 96 Wells
EUR 606
Description: Description of target: Tyrosine-protein kinase receptor UFO is an enzyme that in humans is encoded by the AXL gene. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia-associated oncogene and also associated with colon cancer and melanoma. It is in close vicinity to the bcl3 oncogene, which is at 19q13.1-q13.2. The Axl gene is evolutionarily conserved between vertebrate species. This gene has two different alternatively spliced transcript variants.;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL

Mouse AXL HEK293 Overexpression Lysate
MBS8116399-03mg 0.3mg
EUR 280

Mouse AXL HEK293 Overexpression Lysate
MBS8116399-5x03mg 5x0.3mg
EUR 1205

Mouse AXL HEK293 Overexpression Lysate
MBS8116400-03mg 0.3mg
EUR 280

Mouse AXL HEK293 Overexpression Lysate
MBS8116400-5x03mg 5x0.3mg
EUR 1205

Nori® Mouse Axl ELISA Kit
GR117424 96-well
EUR 461

Mouse Axl Antibody (N-term) Blocking Peptide
MBS9221369-INQUIRE INQUIRE Ask for price

Mouse AXL Protein, Fc & His Tag
E40MOP1138 20ug
EUR 495

AXL Matched ELISA Antibody Pair Set, Mouse
MBS8118476-15Plates 15Plates
EUR 600

AXL Matched ELISA Antibody Pair Set, Mouse
MBS8118476-5Plates 5Plates
EUR 345

AXL Matched ELISA Antibody Pair Set, Mouse
MBS8118476-5x15Plates 5x15Plates
EUR 2755

Mouse AXL ELISA Kit PicoKine®
EK0660 96 wells
EUR 499
Description: Mouse AXL ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Axl in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Anti-Human Axl Antibody
101-M222 100 µg
EUR 399
Description: Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt), and Mer (human and mouse homologues of chicken cEyk) constitute a subfamily of the receptor tyrosine kinases. The extracellular domains of these proteins contain two Iglike motifs and two fibronectin type III motifs. This characteristic topology is also found in neural cell adhesion molecules and in receptor tyrosine phosphatases. The human Axl cDNA encodes an 887 amino acid (aa) precursor that includes an 18 aa signal sequence, a 426 aa extracellular domain, a 21 aa transmembrane segment, and a 422 aa cytoplasmic domain. The extracellular domains of human and mouse Axl share 81% aa sequence identity. A short alternately spliced form of human Axl is distinguished by a 9 aa deletion in the extracellular juxtamembrane region. These receptors bind the vitamin K dependent protein growth arrest specific gene 6 (Gas6) which is structurally related to the anticoagulation factor protein S. Binding of Gas6 induces receptor autophosphorylation and downstream signaling pathways that can lead to cell proliferation, migration, or the prevention of apoptosis. This family of tyrosine kinase receptors is involved in hematopoiesis, embryonic development, tumorigenesis, and regulation of testicular functions.

Recombinant Mouse Axl, Fc-His tagged
Axl-132M 50 µg
EUR 478.4
Description: Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

AXL mouse monoclonal antibody, clone 7E10, Ascites
AM06326SU-N 100 µl Ask for price

Anti-AXL Antibody (FITC), Mouse Monoclonal
MBS8102089-100Tests 100Tests
EUR 245

Anti-AXL Antibody (FITC), Mouse Monoclonal
MBS8102089-25Tests 25Tests
EUR 175

Anti-AXL Antibody (FITC), Mouse Monoclonal
MBS8102089-5x100Tests 5x100Tests
EUR 955

AXL mouse monoclonal antibody, clone 1B3A2, Ascites
AM06260SU-N 100 µl Ask for price

Lenti ORF particles, Axl (GFP-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 1, 200ul, >10^7 TU/mL
MR211073L2V 200 µl Ask for price

Lenti ORF particles, Axl (GFP-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 1, 200ul, >10^7 TU/mL
MR211073L4V 200 µl Ask for price

Lenti ORF particles, Axl (GFP-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 2, 200ul, >10^7 TU/mL
MR222556L4V 200 µl Ask for price

Lenti ORF particles, Axl (GFP-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 3, 200ul, >10^7 TU/mL
MR222558L4V 200 µl Ask for price

Recombinant Mouse AXL protein, His-tagged
Axl-626M 100 µg
EUR 398.4
Description: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

OKBB00412-96W - AXL ELISA Kit (Mouse)
OKBB00412-96W 96Wells
EUR 538

OKRC01096-96W - Axl ELISA Kit (Mouse)
OKRC01096-96W 96Wells
EUR 525

AXL Protein, Mouse, Recombinant (His Tag)
E45M52640M2-100 100 ug
EUR 1046.77

AXL Protein, Mouse, Recombinant (His Tag)
MBS8122549-01mg 0.1mg
EUR 395

AXL Protein, Mouse, Recombinant (His Tag)
MBS8122549-5x01mg 5x0.1mg
EUR 1635

Axl sgRNA CRISPR Lentivector set (Mouse)
K4394001 3 x 1.0 ug
EUR 406.8

Lenti ORF particles, Axl (Myc-DDK-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 1, 200ul, >10^7 TU/mL
MR211073L1V 200 µl Ask for price

Lenti ORF particles, Axl (Myc-DDK-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 1, 200ul, >10^7 TU/mL
MR211073L3V 200 µl Ask for price

Lenti ORF particles, Axl (Myc-DDK-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 2, 200ul, >10^7 TU/mL
MR222556L3V 200 µl Ask for price

Lenti ORF particles, Axl (Myc-DDK-tagged) - Mouse AXL receptor tyrosine kinase (Axl), transcript variant 3, 200ul, >10^7 TU/mL
MR222558L3V 200 µl Ask for price

Recombinant Mouse AXL protein, C-His tag
IMP-801 10µg
EUR 288
Description: Recombinant Proteins

Recombinant Mouse AXL protein, C-hFc tag
IMP-880 10µg
EUR 360
Description: Recombinant Proteins

Rabbit Anti-Mouse AXL protein IgG-Biotinylated
AXL11-BTN 100 ul
EUR 634.8

Axl Protein Vector (Mouse) (pPM-C-HA)
PV157852 500 ng
EUR 1278

Axl Protein Vector (Mouse) (pPM-C-HA)
PV157856 500 ng
EUR 1278

Axl Protein Vector (Mouse) (pPM-C-HA)
PV157860 500 ng
EUR 1278

Mouse AXL Receptor Tyrosine Kinase ELISA kit
E01A19041 96T
EUR 700
Description: ELISA

Recombinant Mouse Axl Kinase Protein (His tag)
MBS2547147-01mg 0.1mg
EUR 685

Recombinant Mouse Axl Kinase Protein (His tag)
MBS2547147-5x01mg 5x0.1mg
EUR 3080

Mouse AXL Receptor Tyrosine Kinase ELISA Kit
MBS7269755-10x96StripWells 10x96-Strip-Wells
EUR 5685

Mouse AXL Receptor Tyrosine Kinase ELISA Kit
MBS7269755-48StripWells 48-Strip-Wells
EUR 485

Mouse AXL Receptor Tyrosine Kinase ELISA Kit
MBS7269755-5x96StripWells 5x96-Strip-Wells
EUR 3020

Mouse AXL Receptor Tyrosine Kinase ELISA Kit
MBS7269755-96StripWells 96-Strip-Wells
EUR 690

Recombinant Mouse Axl Kinase Protein (His Tag)
PKSM040849-100ug 100ug
EUR 732
Description: Mouse

Axl Protein Vector (Mouse) (pPB-C-His)
PV157850 500 ng
EUR 1278

Axl Protein Vector (Mouse) (pPB-N-His)
PV157851 500 ng
EUR 1278

Axl Protein Vector (Mouse) (pPM-C-His)
PV157853 500 ng
EUR 1278

Axl Protein Vector (Mouse) (pPB-C-His)
PV157854 500 ng
EUR 1278

Axl Protein Vector (Mouse) (pPB-N-His)
PV157855 500 ng
EUR 1278

Axl Protein Vector (Mouse) (pPM-C-His)
PV157857 500 ng
EUR 1278

Axl Protein Vector (Mouse) (pPB-C-His)
PV157858 500 ng
EUR 1278

Axl Protein Vector (Mouse) (pPB-N-His)
PV157859 500 ng
EUR 1278

Axl Protein Vector (Mouse) (pPM-C-His)
PV157861 500 ng
EUR 1278

AXL Protein, Mouse, Recombinant (His & hFc Tag)
E45M53389M4-100 100 ug
EUR 1046.77

AXL Protein, Mouse, Recombinant (His & hFc Tag)
MBS8122548-01mg 0.1mg
EUR 395

AXL Protein, Mouse, Recombinant (His & hFc Tag)
MBS8122548-5x01mg 5x0.1mg
EUR 1635

Axl sgRNA CRISPR Lentivector (Mouse) (Target 1)
K4394002 1.0 ug DNA
EUR 184.8

Axl sgRNA CRISPR Lentivector (Mouse) (Target 2)
K4394003 1.0 ug DNA
EUR 184.8

Axl sgRNA CRISPR Lentivector (Mouse) (Target 3)
K4394004 1.0 ug DNA
EUR 184.8

Rabbit Anti-Mouse AXL protein IgG, aff pure
AXL11-A 100 ul
EUR 578.4

Sheep Polyclonal anti-human AXL
hAP-5038 50ug
EUR 400

Rabbit Anti-Mouse AXL monoclonal antibody, clone S210
CABT-ZB554 50 μl
EUR 520
Description: Rabbit

Rabbit Anti-Mouse AXL monoclonal antibody, clone S126
CABT-ZB916 50 μl
EUR 520
Description: Rabbit

Recombinant Mouse Axl Kinase Protein (His & Fc tag)
MBS2547148-01mg 0.1mg
EUR 685

Recombinant Mouse Axl Kinase Protein (His & Fc tag)
MBS2547148-5x01mg 5x0.1mg
EUR 3080

Recombinant Mouse Axl Kinase Protein (His & Fc Tag)
PKSM040850-100ug 100ug
EUR 732
Description: Mouse

Recombinant Mouse Axl Protein, His (Fc)-Avi-tagged
Axl-10522M 50ug
EUR 2398.4
Description: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.

AXL Antibody
MBS7105969-005mg 0.05mg
EUR 190

AXL Antibody
MBS7105969-01mg 0.1mg
EUR 270

AXL Antibody
MBS7105969-5x01mg 5x0.1mg
EUR 1205

AXL Antibody
MBS7120259-005mg 0.05mg
EUR 150

AXL Antibody
MBS7120259-01mg 0.1mg
EUR 190

AXL Antibody
MBS7120259-5x01mg 5x0.1mg
EUR 845

AXL Antibody
MBS7122744-005mg 0.05mg
EUR 150

AXL Antibody
MBS7122744-01mg 0.1mg
EUR 190

AXL Antibody
MBS7122744-5x01mg 5x0.1mg
EUR 845

AXL antibody
10R-1995 100 ul
EUR 374
Description: Mouse monoclonal AXL antibody

AXL antibody
10R-2051 100 ul
EUR 468
Description: Mouse monoclonal AXL antibody

Axl Antibody
39365-100ul 100ul
EUR 468

AXL antibody
70R-9655 50 ug
EUR 467
Description: Affinity purified rabbit polyclonal AXL antibody

AXL Antibody
CAC11246-100ug 100ug
EUR 314

AXL Antibody
CAC11246-50ug 50ug
EUR 199.2

AXL antibody
70R-51253 100 ul
EUR 286
Description: Purified Polyclonal AXL antibody

AXL Antibody
48205 100ul
EUR 429

AXL Antibody
48205-100ul 100ul
EUR 399.6

AXL Antibody
48205-50ul 50ul
EUR 286.8

Axl Antibody
B8079-100ul 100μl
EUR 217
Description: Axl Rabbit Polyclonal Antibody

Axl Antibody
B8079-50ul 50μl
EUR 143.5
Description: Axl Rabbit Polyclonal Antibody

Axl Antibody
B9007-100ul 100μl
EUR 217
Description: Axl Rabbit Polyclonal Antibody

Axl Antibody
B9007-50ul 50μl
EUR 143.5
Description: Axl Rabbit Polyclonal Antibody

AXL Antibody
BF0290 200ul
EUR 540

AXL Antibody
BF0290-100ul 100ul
EUR 210
Description: WB,IF/ICC,ELISA

AXL Antibody
BF0290-200ul 200ul
EUR 270
Description: WB,IF/ICC,ELISA

AXL Antibody
BF0290-50ul 50ul
EUR 150
Description: WB,IF/ICC,ELISA

AXL Antibody
AF7793 200ul
EUR 540

AXL Antibody
AF7793-100ul 100ul
EUR 210
Description: WB,IHC,IF/ICC,ELISA(peptide)

We assume that this is actually a double oxidation mechanically different from the single oxidation is observed and that the high stress conditions support the oxidation mechanism of double (and double oxidation sensitive tryptophan residue) whereas the single oxidation appears to be the main mode of H2O2 oxidation under pressure and length of a term thermal stability and favors a different tryptophan residues are more prone to oxidation mechanism single.

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